Hypertension

FACTS ABOUT HIGH BLOOD PRESSURE

Hypertension is one of the commonest problems that is encountered in the medical consultation. The following are some of the facts.

  • More hypertensives are men than women.
  • The older you are, the higher the chance that you have hypertension.
  • In most of the cases, no specific cause is identified. In some cases, it may be related to renal disease, hormonal disturbances and drugs (eg prednisolone, OC pill).
  • The usual cut-off point for hypertension is 140/90 mmHg for adults, but hypertension should not be diagnosed on the basis of a single reading. Initial elevated readings should be confirmed on at least two follow-up visits.
  • Hypertension often is asymptomatic; most of the cases are diagnosed incidentally. Some people will experience dizziness, headaches, nose bleeding and paraesthesia of limbs.
  • Hypertension can harm the kidneys, heart and cerebrovascular system. It accounts for 5% of ESRF in Hong Kong. Kidney disease in turn can cause hypertension.
  • Uncontrolled or poorly controlled high blood pressure is a common cause of renal failure.
  • Renal manifestation of hypertension include
    • proteinuria
    • renal impairment
  • Primary prevention of hypertension documented efficacy:
    • dietary sodium reduction
    • alcohol moderation
    • weight loss
    • physical activity
    • potassium supplementation unproven efficacy
    • stress management
    • calcium, magnesium, fish oil and dietary fiber supplementation
    • caffeine consumption moderation
    • reduced dietary saturated-to-polyunsaturated fat ratio
  • Hypertension can be treated by lifestyle modification (similar to the primary prevention of hypertension) and medications

Diabetic Nephrology

FACTS ABOUT DIABETES AND KIDNEY DISEASE

  • Diabetes mellitus accounts for 21% of ESRF in Hong Kong
  • There are different types of diabetes :
    • the most common are:
    • Type 1, which is caused by an inability of the pancreas to produce insulin, either autoimmune or idiopathic;
    • Type 2, which range from predominantly insulin resistance with relative insulin deficiency to a predominantly secretory defect with or without insular resistance
  • Diabetes damages blood vessels throughout the body, affecting the kidneys, coronary arteries, cerebrovascular system and nerves
  • Common renal problems in diabetes include
    • diabetic nephropathy
    • renal (ischemic) disease (renal artery stenosis, cholesterol embolism)
    • urinary tract infection
    • papillary necrosis
    • contrast nephropathy (if diabetic patients undergo contrast investigation)
  • Symptoms and signs that a diabetic patient may be developing kidney disease include:
    • Proteinuria
    • leg swelling
    • hypertension
    • uremic symptoms (nausea, vomiting)
    • anaemia
    • itching
    • hypoglycaemic attack (because of reduced requirement of insulin as kidney fails)
  • Natural history of diabetic nephropathy
    • asymptomatic ® microalbuminuria ® significant ® renal impairment ®and-stage renal failure
  • Prevention of diabetic nephropathy
    • controlling high blood pressure
    • controlling blood sugar level
    • reduction of dietary protein intake
    • correct hyperlipidamia
    • stop smoking
    • avoid medications that damage kidneys
  • Long-term renal replacement therapy for diabetics includes peritoneal dialysis, haemodialysis kidney transplantation and combined kidney-pancreas transplantation. The optimal mode of treatment will be determined by the general health, medical conditions, personal preference and the availability of resources
Copyright@1999. Hong Kong Kidney Foundation Ltd. All right reserved.
Created by Tse Tak Yee 1999